Summary of an article in the Lancet
Obesity and its metabolic complications, including diabetes, have been associated with an increased risk of several cancers.1 The global obesity epidemic has fuelled a sustained rise in obesity-related cancers, especially in resource-poor regions with few options for population-based screening. Thus, the potential use of metformin as a novel cancer prevention strategy has generated much excitement in view of its low cost, favourable safety profile, and its potential for biological specificity in disrupting the association between obesity and cancer.
Obesity and its metabolic complications, including diabetes, have been associated with an increased risk of several cancers.1 The global obesity epidemic has fuelled a sustained rise in obesity-related cancers, especially in resource-poor regions with few options for population-based screening. Thus, the potential use of metformin as a novel cancer prevention strategy has generated much excitement in view of its low cost, favourable safety profile, and its potential for biological specificity in disrupting the association between obesity and cancer.