Statins double risk of diabetes.

The research, published in a leading journal examined 25,970 patients over ten years and discovered statin users had a higher incidence of diabetes and also weight gain.

Patients using the drugs also had more than double the risk of diabetic complications including eye, nerve and kidney damage.

Scientists say the new research published in the leading Journal of General Internal Medicine, confirms a long suspected link between statin use and diabetes.

Professor Ishak added: “There is not enough funding to carry out studies to assess these long term effects that are not funded by drug companies and therefore clouded by conflicts of interest.”

And he said drugs may be doing more harm than good for people at low risk of heart disease: “I am sceptical about the prescribing guidelines for people at lower risk (of heart disease). I am concerned about the long term effects on the huge population of healthy people on these drugs who continue for many years.”

And Dr Malcolm Kendrick, who has studied statins and heart health said: “There have been a number of small studies that have suggested an increase in the risk of diabetes and statin use. However this large and long term study has confirmed this is a significant problem. “

He added: “This study demolishes the argument that these drugs should be prescribed to anyone, as the harms may outweigh previously suggested benefits.”

More on this story here.

http://www.express.co.uk/life-style/health/639586/Statins-doubles-diabetes-study-drug

Note

"Patients using the drugs also had more than double the risk of diabetic complications including eye, nerve and kidney damage"

What with the ludicrous diets we are told to follow, and doubling our already high risk of complications, it's a wonder any of us last very long. Maybe that's the plan, how good it would be if the peasants all croaked a year or two before retirement. Yes, that's the way forward, meds from the cradle to an early grave, scoffing low nutrient fodder from a petro-chem plant. Living in £200k home not much bigger than a jail cell, and spending all disposable income on cheap Chinese shite.

Nah, people wouldn't fall for that, would they?

Yes I'm sure we have seen longevity peak and it will now begin to fall. There are further "epidemics" of Alzheimers etc. waiting in the wings too.

From the drug companies' POV, so what, anything bad that statins do means a market for one of our other drugs. Anyway PCSK9 inhibitors are SO MUCH BETTER!!!

Professor Rory Collins, whose research helped rubber stamp statins as safe, told this paper in a previous statement his team will carry out a “challenging” reassessment of the evidence which will include studying all reported side effects.

However he warned fears over side effects may be putting high risk heart disease patients at risk and cost lives. He argued the side effects are far outweighed by the benefits for those at risk of heart disease.

Right the dubious benefits of statins far outweigh the risks of diabetes, irreversible muscle breakdown, muscle pain, blood disorders, diabetes, skin disorders, nervous system disorders and stomach problems. 

But apart from that what have the Romans, er  statins, ever done for us?

It's so entertaining re-reading the past, it's like deja vu all over again. 

Here is an especially sarcastic post from Michael Eades from over 8 years ago.

Steven Nissen of Cleveland Clinic  is the American Statinator in Chief, I was trying to remember his name to go alongside Sir Rory Statin, er Collins (any relation to Catherine Collins the dreadful dietician?). Pity he isn't equally fat or you could call him Nissen The Hutt.

I think there's SOME evidence that statins MAY be useful for middle aged men who have already had a heart attack, little for anyone else and none whatsoever for women. But that's not a big enough market so they have been pushed on everyone, and now that Collins & co. have been outed as sitting on all the negative data from trials, the cows are coming home to roost.

ps. you missed out replacing cardiovascular disease with heart failure, that's a bit of a big own goal . . .

chris c wrote:But apart from that what have the Romans, er  statins, ever done for us?

It's so entertaining re-reading the past, it's like deja vu all over again. 

Here is an especially sarcastic post from Michael Eades from over 8 years ago.

Steven Nissen of Cleveland Clinic  is the American Statinator in Chief, I was trying to remember his name to go alongside Sir Rory Statin, er Collins (any relation to Catherine Collins the dreadful dietician?). Pity he isn't equally fat or you could call him Nissen The Hutt.

I think there's SOME evidence that statins MAY be useful for middle aged men who have already had a heart attack, little for anyone else and none whatsoever for women. But that's not a big enough market so they have been pushed on everyone, and now that Collins & co. have been outed as sitting on all the negative data from trials, the cows are coming home to roost.

ps. you missed out replacing cardiovascular disease with heart failure, that's a bit of a big own goal . . .

Latest from Sir Rory Statin 

Protocol for analyses of adverse event data from randomized controlled trials of statin therapy


Snip

The Cholesterol Treatment Trialists’ (CTT) Collaboration involves the principal investigators and sponsors responsible for conducting around 30 large randomized trials of statin therapy in about 200,000 people. For its previous analyses, the outcome data obtained on individual patients in these trials were limited to major vascular events, site-specific cancers and cause-specific mortality.1 As no comprehensive summary of the effects of statins on all recorded adverse events is currently available to prescribers and patients, the present protocol describes plans to seek individual participant data on all of the other adverse events recorded in eligible trials for detailed analyses.

Funding

The CTT Collaboration work has received grants from government (UK Medical Research Council and Australian National Health and Medical Research Council) and from charities (British Heart Foundation, Cancer Research UK, and Australian National Heart Foundation), but not from the pharmaceutical industry. Although most of the trials that will contribute to these analyses were supported (at least in part) by research grants from the pharmaceutical industry, most of them were conducted, analysed, interpreted and reported independently of all funding sources by academic investigators.

http://www.ahjonline.com/article/S0002-8703(16)00032-6/fulltext

Details of CTT funding here: [url=http://journals.bmj.com/site/bmj/statins/SP21 CTSU grants May 2014.pdf]http://journals.bmj.com/site/bmj/statins/SP21%20CTSU%20grants%20May%202014.pdf[/url]

graham64 wrote:

Protocol for analyses of adverse event data from randomized controlled trials of statin therapy

Asshat. He's been sitting on this data refusing to release it for YEARS now.