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THE LOW CARB DIABETIC

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    Novo brings Xultophy to third European market (UK)

    graham64
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    Novo brings Xultophy to third European market (UK) Empty Novo brings Xultophy to third European market (UK)

    Post by graham64 on Mon Jun 08 2015, 22:46

    Novo Nordisk has launched its diabetes drug Xultophy (insulin degludec and liraglutide) in the UK, following its arrival earlier this year in Germany and Switzerland.

    Xultophy combines Novo's blockbuster GLP-1 receptor agonist Victoza (liraglutide)  with its new long-acting insulin Tresiba (insulin degludec) in a once-daily injection for type 2 diabetes.

    Speaking to PMLiVE at the American Diabetes Association's 75th Scientific Sessions in Boston, Novo 's EVP for China, Pacific and Marketing Jakob Riis said Xultophy was being given a “classic diabetes launch”.

    Within the European Union this means coming to Germany and the UK first, with other countries following once their market access and reimbursement positions are clarified.

    He added: “It's early days [with the Swiss and Germany launches], but we are very pleased. The reception in the market place has fully lived up to our expectations that there's excitement around Xultophy as a new treatment option.

    “And, though it's still very early days, we've seen good uptake and that makes us very positive about the future.” 

    The combination will priced lower than the sum of its individual parts in the UK as it has in Switzerland  and Germany. Riis said Novo planned to follow this principle for Xultophy's future European launches.
     

     Asked whether Xultophy would erode sales of Victoza, which brought in $2.3bn last year, Riis said the two products would be able to co-exist because there would always be a market for getting 'the job done' with just a GLP-1 receptor agonist.

    “In the long run Xultophy will not take sales away from Victoza, because the type 2 market is so big and we treat only a couple of per cent of patients with Victoza. So, we're not in the situation where there's not room for both brands to create a very, very strong position.

    “We do see that some patients that have been on both an insulin and Victoza, some of those may be converted to get it in one injection. But that's only a transitional issue, in the longer run the two products will do very, very well side by side.”

    The combination - previously known as iDeglira - received European approval  in September to improve adults' glycaemic control in combination with oral glucose-lowering medicinal products when these alone or combined with basal insulin do not provide adequate glycaemic control.

    It's European roll-out continues in the face of continued uncertainty about the product's position in the US, due to FDA approval delays for the Tresiba component.

    US regulators dealt the company a major blow in February 2013 when marketing applications for Tresiba and Ryzodeg, which combines Tresiba with Novo's Novolog (insulin aspart), were rejected.

    The FDA began a fresh review of the two diabetes drugs  in April and the regulator is due to make a decision on their latest approval submission by 1 October.

    http://www.pmlive.com/pharma_news/novo_brings_diabetes_drug_xultophy_to_third_european_market_752493

    Another in a long list of new T2 drugs introduced to the UK, with the present dietary guidelines the futures looking rosy for Big Pharma


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    Not all cherubs are Angels  Wink nor all diabetics Bonkers  Rolling Eyes
    zand
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    Post by zand on Tue Jun 09 2015, 08:44



    “We do see that some patients that have been on both an insulin and Victoza, some of those may be converted to get it in one injection. But that's only a transitional issue, in the longer run the two products will do very, very well side by side.”

    I've picked out just one section, but I interpret the whole message to be:-
    Why help patients to be drug free when we can make money out of them? Why give them just one drug when they can have two?

    Or did I get that wrong?
    Eddie
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    Post by Eddie on Tue Jun 09 2015, 13:15

    @zand wrote:

    “We do see that some patients that have been on both an insulin and Victoza, some of those may be converted to get it in one injection. But that's only a transitional issue, in the longer run the two products will do very, very well side by side.”

    I've picked out just one section, but I interpret the whole message to be:-
    Why help patients to be drug free when we can make money out of them?  Why give them just one drug when they can have two?

    Or did I get that wrong?  

    No you did not get it wrong, another junk type two med no one needs. Google Victoza and you will find lots of negative side effects, and the legal cases are building up in the US. This is a game played by big pharma to keep the patented drugs going. Add an ingredient etc and get another ten years of high sales. Make $ten billion, get fined or compensate $2 billion trouser $8 billion that's how it often works. Every one does well, except the cannon fodder diabetics.


    _________________
    Type two diabetic-low carb diet (50 carbs per day) and two 500mg Metformin pills per day. Apart from diagnosis HbA1c almost 12-all HbA1c results none diabetic. For over eight years my diabetes medication has not changed. My weight has remained stable, I have suffered no ill effects from my diet whatsoever. Every blood test has proved, I took the right road to my diabetic salvation. For almost seven years, I have asked medical professionals and naysayers, how do I maintain non diabetic BG levels on two Metformin other than low carb ? The silence has been deafening !
    zand
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    Post by zand on Tue Jun 09 2015, 14:43

    Yep exactly that. Even more people are becoming T2 and/or obese because of mainstream NHS and DUK dietary advice, so there's plenty more cannon fodder being produced for greedy big pharma.

    graham64
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    Post by graham64 on Tue Jun 09 2015, 22:19

    Not content with over medicating Type 2 diabetics with possibly harmful drugs Big Pharma are now targeting Type 1s with a triple therapy.

     Triple therapy improves glycemia in type 1 diabetes

    The combination of insulin, a GLP-1 receptor agonist and an SGLT-2 inhibitor significantly improved glycemia in patients with type 1 diabetes, according to late-breaking data presented at the American Diabetes Association’s 75th Scientific Sessions

    http://www.healio.com/endocrinology/



    _________________
    I'm a skinny T2 diagnosed 4/4/2008, a high calorie LCHF diet and one metformin a day A1c 6.2 and no complications.

    Proving the LowCarb sceptics wrong for over ten years

    Not all cherubs are Angels  Wink nor all diabetics Bonkers  Rolling Eyes
    zand
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    Post by zand on Wed Jun 10 2015, 09:16

    If it wasn't so evil this would be funny.  OK Big Pharma is greedy for money.  I get that.  What I don't get is the willingness of a group of people who have signed the Hippocratic oath to prescribe more drugs which will eventually harm patients.  

    "And I will use treatments for the benefit of the ill in accordance with my ability and my judgment, but from what is to their harm and injustice I will keep them."

    I suppose the important phrase here is "ability and judgement".  Maybe too many patients readily accept the ability and judgement of their doctors without even questioning it.

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