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Hydrogen: an Emerging Medical Gas
(complete article on link)
http://www.molecularhydrogeninstitute.com/hydrogen-an-emerging-medical-gas
HYDROGEN AND IMMEDIATE MEDICAL APPLICATIONS
Hydrogen as a medical gas is also growing because it has immediate medical applications to help with many of the current health crises [65, 66]. Dixon and colleagues of Loma-Linda University reported that hydrogen has potential to help with the top 8/10 disease-causing fatalities as listed by the Centers of Disease Control [67]. Dr. Banks,from the VA/U of Washington, reported that ingestion of hydrogen-rich water was protective against neurodegenerative changes induced by traumatic brain injury in mice [68]. Their results show that hydrogen administration reduced brain edema, blocked pathological tau expression, and maintained ATP levels. This and other studies have profound effects for events where brain injury (e.g. concussion, chronic traumatic encephalopathy, etc.) is a common occurrence [69]. Although many people report dramatic effects of hydrogen therapy, from rapid pain and inflammation relief to normalization of glucose and cholesterol levels, other people may not notice any immediate or observable benefits. Hydrogen is not considered a powerful drug, and as mentioned only helps bring the cell/organ back to homeostasis without causing major perturbations. Perhaps some of the reported dramatic effects can be attributed to the placebo effect or other things, although some researchers have noted that some people are more sensitive to hydrogen and experience greater effects. More human studies are needed to answer these questions.
HUMAN RESEARCH
Although the research on hydrogen looks promising in the cell or animal models, more long-term clinical trials are required to confirm its efficacy in humans [70]. There are only a total of 40 human studies; few are in a double-blinded placebo controlled randomized fashion with sufficient subject numbers. A few of these clinical studies suggest that ingestion of hydrogen-rich water was beneficial for metabolic syndrome [71], diabetes [72], and hyperlipidemia [73, 74]. Another 1-year placebo-control clinical study suggested that hydrogen-rich water is beneficial for Parkinson’s disease [75], while other clinical studies suggest significant benefits for rheumatoid arthritis [24, 76], mitochondrial dysfunction [77], exercise performance [78], athletic recovery time [79], wound healing [80-82], reductions of oxidative stress from chronic hepatitis B [83], improvements to blood flow [84], and periodontitis [85], in dialysis [86, 87], and also the quality of life in patients receiving radiotherapy for tumors [88] and others [5].
There have been an additional 15+ human studies completed with promising results, which are in the process of manuscript preparation and publication through the peer-reviewed process. More human studies are required to determine proper dosage, timing, method of administration, and for which diseases, and potentially genotypes, hydrogen is most effective [7]. Hydrogen is still in its infancy, and more data is required before we can scientifically claim any real benefit, but the preliminary data is intriguing. The research on disease models, mechanisms of action, and clinical studies are particularly relevant because the high safety profile of molecular hydrogen make it a superior choice [89].
(complete article on link)
http://www.molecularhydrogeninstitute.com/hydrogen-an-emerging-medical-gas
HYDROGEN AND IMMEDIATE MEDICAL APPLICATIONS
Hydrogen as a medical gas is also growing because it has immediate medical applications to help with many of the current health crises [65, 66]. Dixon and colleagues of Loma-Linda University reported that hydrogen has potential to help with the top 8/10 disease-causing fatalities as listed by the Centers of Disease Control [67]. Dr. Banks,from the VA/U of Washington, reported that ingestion of hydrogen-rich water was protective against neurodegenerative changes induced by traumatic brain injury in mice [68]. Their results show that hydrogen administration reduced brain edema, blocked pathological tau expression, and maintained ATP levels. This and other studies have profound effects for events where brain injury (e.g. concussion, chronic traumatic encephalopathy, etc.) is a common occurrence [69]. Although many people report dramatic effects of hydrogen therapy, from rapid pain and inflammation relief to normalization of glucose and cholesterol levels, other people may not notice any immediate or observable benefits. Hydrogen is not considered a powerful drug, and as mentioned only helps bring the cell/organ back to homeostasis without causing major perturbations. Perhaps some of the reported dramatic effects can be attributed to the placebo effect or other things, although some researchers have noted that some people are more sensitive to hydrogen and experience greater effects. More human studies are needed to answer these questions.
HUMAN RESEARCH
Although the research on hydrogen looks promising in the cell or animal models, more long-term clinical trials are required to confirm its efficacy in humans [70]. There are only a total of 40 human studies; few are in a double-blinded placebo controlled randomized fashion with sufficient subject numbers. A few of these clinical studies suggest that ingestion of hydrogen-rich water was beneficial for metabolic syndrome [71], diabetes [72], and hyperlipidemia [73, 74]. Another 1-year placebo-control clinical study suggested that hydrogen-rich water is beneficial for Parkinson’s disease [75], while other clinical studies suggest significant benefits for rheumatoid arthritis [24, 76], mitochondrial dysfunction [77], exercise performance [78], athletic recovery time [79], wound healing [80-82], reductions of oxidative stress from chronic hepatitis B [83], improvements to blood flow [84], and periodontitis [85], in dialysis [86, 87], and also the quality of life in patients receiving radiotherapy for tumors [88] and others [5].
There have been an additional 15+ human studies completed with promising results, which are in the process of manuscript preparation and publication through the peer-reviewed process. More human studies are required to determine proper dosage, timing, method of administration, and for which diseases, and potentially genotypes, hydrogen is most effective [7]. Hydrogen is still in its infancy, and more data is required before we can scientifically claim any real benefit, but the preliminary data is intriguing. The research on disease models, mechanisms of action, and clinical studies are particularly relevant because the high safety profile of molecular hydrogen make it a superior choice [89].
