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THE LOW CARB DIABETIC

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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    graham64
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by graham64 Sun Apr 05 2015, 22:02

    This study was published in Steroids 2015 Mar 23

    Study title and authors:
    Increased plant sterol deposition in vascular tissue characterizes patients with severe aortic stenosis and concomitant coronary artery disease.

    Luister A, Schött HF, Husche C, Schäfers HJ, Böhm M, Plat J, Gräber S, Lütjohann D, Laufs U, Weingärtner O.
    Klinik für Innere Medizin III¸Kardiologie, Angiologie und Internistische Intensivmedizin.

    This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/25814070


    Phytosterols are present in very small quantities in fruit and vegetables. The phytosterol content of plant sterol-enriched margarines (Benecol, Flora proactive etc) are higher by an order of magnitude of up to 841 times than the average vegetable (see here). Campesterol and sitosterol are types of phytosterols.

    Oxyphytosterols are phytosterols that have gone rancid.

    Cholestanol is a derivative of cholesterol.

    The aim of the study (of 104 patients) was to evaluate the relationship between phytosterols, oxyphytosterols, lathosterol, cholestanol and cholesterol in patients with severe aortic stenosis (artery blockages), some of whom also had coronary artery disease who were scheduled for elective aortic valve replacement.

    The study found:
    (a) The ratio of campesterol-to-cholesterol was increased by 26% in plasma of patients with coronary artery disease compared to those without coronary artery disease.
    (b) Sitosterol concentrations were increased by 38.8% in the tissues of patients with coronary artery disease compared to those without coronary artery disease.
    (c) Campesterol concentrations were increased by 30.4% in the tissues of patients with coronary artery disease compared to those without coronary artery disease.
    (d) Oxidized sitosterol-to-cholesterol ratios were up-regulated by 22.7% in the plasma of patients with coronary artery disease compared to those without coronary artery disease.
    (e) Oxidized campesterol was increased by 17.1% in the aortic valve cusps (the triangular fold or flap of a heart valve) of patients with coronary artery disease compared to those without coronary artery disease.
    (f) Neither cholestanol nor the ratio of cholestanol-to-cholesterol was associated with coronary artery disease.

    Luister concluded: "Patients with concomitant coronary artery disease are characterized by increased deposition of plant sterols, but not cholestanol in aortic valve tissue. Moreover, patients with concomitant coronary artery disease were characterized by increased oxyphytosterol concentrations in plasma and aortic valve cusps".

    Is it wise to consume margarines high in phytosterols (such as Benecol and Flora proactive) when the study suggests that phytosterols are associated with a higher risk of coronary artery disease?


    http://healthydietsandscience.blogspot.co.uk/
    Paul1976
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Paul1976 Sun Apr 05 2015, 22:19

    Hi Graham! Another nail in the coffin for these frankenshite products that are labelled as health foods eh? Would rather eat 2 week old horseshit off a broken plate then touch these scary science experiments! Wink

    Cheers

    Paul
    Eddie
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Eddie Sun Apr 05 2015, 22:29

    It has been known for years they are a health hazard. From the Dr.Briffa blog http://www.drbriffa.com/2011/04/25/healthy-cholesterol-reducing-compounds-found-to-be-toxic-to-heart-cells/

    ‘Healthy’ cholesterol-reducing compounds found to be toxic to heart cells

    by Dr John Briffa on 25 April 2011 in Healthy Eating, Specific conditions, Unhealthy Eating!
    ‘Phytosterols’ are compounds that can impair the absorption of cholesterol from the gut. In this way, ‘sterols’ (as their name is often abbreviated to) can reduce cholesterol levels in the bloodstream, which conventional wisdom dictates is always a good thing. Sterols are added to ‘functional foods’ including special margarines that promise cholesterol-reducing and, therefore, health-enhancing properties.

    However, the reality is that the impact a drug or foodstuff has on cholesterol levels is quite irrelevant – it’s its impact on health that is important. This distinction is critically important: Arsenic and cyanide might reduce cholesterol levels, but that does not make them healthy things to consume.

    I was interested to read about a recent study in which the effect of sterols on rat heart cells was assessed [1]. The cells were exposed to levels of sterols commonly found in the bodies of individuals ingesting sterols. The cells ended up incorporating the sterols at the expense of cholesterol. However, at the same time, the metabolic activity of the heart cells decreased, as did their capacity for growth. In short, exposing heart cells to sterols appears to, err, poison them.

    The authors point out, that the results of this study cannot necessarily be translated into conclusions about the effect of these compounds on heart health, but add that the findings “raise[s] concerns about the safety of long-term exposure to physiologically relevant PS [phytosterol] concentrations.”

    References:

    1. Danesi F, et al. Phytosterol supplementation reduces metabolic activity and slows cell growth in cultured rat cardiomyocytes. British Journal of Nutrition 20 April 2011 [epub]
    graham64
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by graham64 Sun Apr 05 2015, 22:52

    Paul1976 wrote:Hi Graham! Another nail in the coffin for these frankenshite products that are labelled as health foods eh? Would rather eat 2 week old horseshit off a broken plate then touch these scary science experiments! Wink

    Cheers

    Paul

    The health claims of Flora have been overstated for years, with millions spent on promoting their products people were duped by the claims that their products were healthier than butter when in fact until recently they were loaded with industrial trans fat, now instead they add yet another dubious substance Mad 

    It's not the first time the use of plant sterols have been under the spotlight.
    Mrs Vimes
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Mrs Vimes Mon Apr 06 2015, 07:13

    I was recommended to take these for a while so I did try them then decided naaahhhh!
    Horrifying really. Love the Frankenshite comment. Thanks for drawing attention to this.
    Eddie
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Eddie Mon Apr 06 2015, 09:47

    When did you last see a Flora advert on the box? Unilever have dumped it and trying to sell it off. They know it makes sense and are not going to fight it

    "It spent decades in the nutritional wilderness, blamed for heart disease, high cholesterol, and making people fat. But butter is back – and if you don’t believe us, ask the consumer goods colossus Unilever.

    Billion-pound brands such as Flora have been at the heart of the Anglo-Dutch giant since its inception nearly a century ago. But the appetite for margarine seems to be melting around the world, forcing Unilever to admit defeat in the war against butter.

    Last autumn, the company added butter to one of its spreads for the first time. Last week, Unilever said the move was paying off: although margarine sales were still down during its fourth quarter, shoppers in Germany had “responded  positively” to the new-taste, “butter-based” Rama."

    Only a low carb anti or the average dietitian would eat the junk.

    Link to info http://www.independent.co.uk/life-style/food-and-drink/news/butter-is-back-margarine-giant-admits-defeat-in-the-battle-of-the-spreads-9085486.html
    Mrs Vimes
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Mrs Vimes Mon Apr 06 2015, 10:17

    Now you come to mention it I can't remember the last time I saw a margarine advert.
    Eddie
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Eddie Mon Apr 06 2015, 11:35

    Mrs Vimes wrote:Now you come to mention it I can't remember the last time I saw a margarine advert.

    The genie is out of the bottle and will never go back. People are wise-ing up fast to what is junk and what is real food. All we need to do is re-educate the average dietitian and we have cracked it.
    Mrs Vimes
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Mrs Vimes Mon Apr 06 2015, 11:38

    Good luck with that one. Mine looked just plain shocked when I said the only carbs I ate came from veg. "But we don't count them."
    Paul1976
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Paul1976 Mon Apr 06 2015, 11:42

    It sure as hell beats me why dietitians are so obsessed that we eat 'Beige foods' such as bread,spuds,pasta etc...They contain far less nutrients than the colourful veggies we eat...You'd think they'd be applauding us for eating the colours of the rainbow!
    Paul1976
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Paul1976 Mon Apr 06 2015, 11:45

    graham64 wrote:
    Paul1976 wrote:Hi Graham! Another nail in the coffin for these frankenshite products that are labelled as health foods eh? Would rather eat 2 week old horseshit off a broken plate then touch these scary science experiments! Wink

    Cheers

    Paul

    The health claims of Flora have been overstated for years, with millions spent on promoting their products people were duped by the claims that their products were healthier than butter when in fact until recently they were loaded with industrial trans fat, now instead they add yet another dubious substance Mad 

    It's not the first time the use of plant sterols have been under the spotlight.

    I used to wind Duggie up on the flog about future 'Margarine mountains'...Looks like that's very likely now! Wink
    Jan1
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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

    Post by Jan1 Mon Apr 06 2015, 12:00

    I have seen 'Gold' advertised which apparently is margarine with added butter - I ask you - what is wrong with just butter ........

    flower  Well - I for one am sticking with butter and lard and olive oil .........  flower

    All the best Jan

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    Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease Empty Re: Plant sterols, found in Benecol and Flora proactive, are associated with an increased risk of coronary artery disease

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