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    This Is Why You Are Paid A Salary

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    chris c
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    This Is Why You Are Paid A Salary

    Post by chris c on Wed Sep 26 2018, 23:25

    not a sugary

    Salt Sensitivity Is Associated With Insulin Resistance in Essential Hypertension

    https://academic.oup.com/ajh/article/11/4/397/179139

    actually I think they have this the wrong way round, it's the hyperinsulinemia that messes with the kidneys' ability to control sodium levels

    Long birder
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    Re: This Is Why You Are Paid A Salary

    Post by Long birder on Thu Sep 27 2018, 10:21

    I buy that for the sodium sensitive but there are a number of feedback loops that have to be considered.

    Diabetes does not just have one cause.
    As I said before Conn knew over fifty years ago those with an active adrenal tumour producing aldosterone, many times, but not always, had carbohydrate intolerance and diabetes and retained sodium and also lost potassium.
    Their main problem is severe hypertension due sodium retension and potassium leakage.

    Excess aldosterone messes with the kidneys, heart and every organ system in the body that have adosterone receptors in. It shuts down the process by which potassium improves signalling and instead  stuffs the cells with sodium.

    This is why if salt in normo tensives is cut too much it is bad because it amplifies the aldosterone the adrenals  produce via angiotensin 2. and constricts arteries.

    Phinney recognises this in his writings.
    Derek
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    Re: This Is Why You Are Paid A Salary

    Post by chris c on Fri Sep 28 2018, 23:09

    Yes it's a balancing act, and there's another one between calcium and magnesium which is also complicated by vitamin D3 and K2. We evolved some pretty complex interactions compared to the simplistic dogma that is preached.

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    Re: This Is Why You Are Paid A Salary

    Post by Long birder on Sat Sep 29 2018, 10:38

    Didn't realise the recent findings show that for carbohydrate eaters insulin resistance converts 30% of the carb produced glucose to fructose whereas in non insulin resistant individuals it's 3%!
    D.


    Last edited by Long birder on Sun Sep 30 2018, 22:29; edited 1 time in total
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    Re: This Is Why You Are Paid A Salary

    Post by chris c on Sun Sep 30 2018, 21:40

    That's interesting, fructose in quantity can be pretty nasty stuff as it bypasses some of the control mechanisms. Probably useful to gain weight for the winter when it was seasonal, not so much when in overdose the year round like today.

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