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    More Science, Can You Believe It?

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    chris c
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    Re: More Science, Can You Believe It?

    Post by chris c on Thu Nov 01 2018, 22:35

    I'll read that later after I've eaten some cheese.
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    graham64
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    Re: More Science, Can You Believe It?

    Post by graham64 on Fri Nov 02 2018, 22:44

    Spotted this on twitter unfortunately the full text is not available yet 

     High low-density lipoprotein cholesterol inversely relates to dementia in community-dwelling older adults

    Abstract

    Background: The relationship between cholesterol and cognitive function is unclear from the previous studies. This study was conducted to explore this association in older Chinese adults.

    Methods: Data were from the Shanghai Aging Study, comprising 3836 residents aged 50 years or over in an urban community. Diagnoses of dementia and mild cognitive impairment were established according to the fourth edition of diagnostic and statistical manual of mental disorders (DSM-IV) and Petersen criteria. Multivariate logistic regression models, non-matched and propensity score (PS) matched, were used to examine the association between cholesterol levels and cognitive function.

    Results: There was a significantly higher proportion of participants with low levels of total cholesterol (TC) and low density lipoprotein cholesterol(LDL-C) in the dementia group than in groups without dementia (P<0.05). High LDL-C level was inversely associated with dementia, with a negative trend in the PS matched model. TC and high density lipoprotein cholesterol (HDL-C) were not significantly related to dementia in either non-matched models or PS matched models.

    Conclusion: Our result indicates that high level of LDL-C is inversely associated with dementia. High level of LDL-C may be considered as a potential protective factor against cognition decline.

    https://www.frontiersin.org/articles/10.3389/fneur.2018.00952/abstract

    Could statins be playing a part in increasing the risks of dementia as well


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    I'm a skinny T2 diagnosed 4/4/2008, a high calorie LCHF diet and one metformin a day A1c 6.2 and no complications.

    Proving the LowCarb sceptics wrong for over ten years

    Not all cherubs are Angels  Wink nor all diabetics Bonkers  Rolling Eyes
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    Re: More Science, Can You Believe It?

    Post by chris c on Sun Nov 04 2018, 22:54

    I found the full paper here

    http://sci-hub.tw/10.3389/fneur.2018.00952

    need to read it later.

    I've actually seen statins recommended for Alzheimers. Probably washed down with Coca-Cola.

    Meanwhile, have a cow

    OF COWS AND MEN: REVIEWING THE LINK BETWEEN
    MILK FAT AND HUMAN HEALTH

    https://ecommons.cornell.edu/bitstream/handle/1813/59846/Rico%20(manu).pdf?sequence=2

    Saturated Fat: Part of a Healthy Diet
    Victoria M. Gershuni1

    http://sci-hub.tw/https://doi.org/10.1007/s13668-018-0238-x

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    Re: More Science, Can You Believe It?

    Post by chris c on Fri Nov 09 2018, 00:25

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    graham64
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    Re: More Science, Can You Believe It?

    Post by graham64 on Fri Nov 09 2018, 22:06


    The All-Party Parliamentary Group recommendations look promising, if they ever get off the ground that would go a long way to reducing the billion spent on diabetes drugs 


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    Proving the LowCarb sceptics wrong for over ten years

    Not all cherubs are Angels  Wink nor all diabetics Bonkers  Rolling Eyes
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    Re: More Science, Can You Believe It?

    Post by chris c on Sun Nov 11 2018, 22:33

    From what I recall David Unwin alone is now saving over £50 000/year - and no use of expensive slop

    https://twitter.com/DrScottMurray/status/1046505750686826498

    it seems what he listed isn't the actual slop used, just a similar one.

    Did I do this one yet?

    Haemoglobin A1c even within non-diabetic level
    is a predictor of cardiovascular disease in a general
    Japanese population: the Hisayama Study

    https://cardiab.biomedcentral.com/track/pdf/10.1186/1475-2840-12-164

    follows on from some of the classic studies like EPIC-Norfolk

    Study on the levels of glycosylated lipoprotein in patients with
    coronary artery atherosclerosis

    https://sci-hub.tw/10.1002/jcla.22650

    I haven't yet psyched myself up to watch the interview of Dave Feldman and Peter Attia, in fact I probably won't, life's too short. Attia and Dayspring are all about lowering LDL, this is yet another study that shows the problem is DAMAGED LDL. It'll never catch on though, we don't have a drug for that.

    Glucagon is the key factor in the development of diabetes

    https://link.springer.com/content/pdf/10.1007%2Fs00125-016-3965-9.pdf

    another from Roger Unger et al.

    Identifying hyperinsulinaemia in the absence of impaired glucose tolerance:
    An examination of the Kraft database

    https://www.researchgate.net/publication/304535127_Identifying_hyperinsulinaemia_in_the_absence_of_impaired_glucose_tolerance_An_examination_of_the_Kraft_database

    a tribute to Joseph Kraft
    and an original

    https://pharmacistcatherinedotnet.files.wordpress.com/2017/02/kraft-1975.pdf
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    graham64
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    Re: More Science, Can You Believe It?

    Post by graham64 Yesterday at 22:49

    Just published today

    Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

    Conclusions Consistent with the carbohydrate-insulin model, lowering dietary carbohydrate increased energy expenditure during weight loss maintenance. This metabolic effect may improve the success of obesity treatment, especially among those with high insulin secretion.

    https://www.bmj.com/content/363/bmj.k4583

    High Low-Density Lipoprotein Cholesterol Inversely Relates to Dementia in Community-Dwelling Older Adults: The Shanghai Aging Study

    Conclusion: Our result indicates that high level of LDL-C is inversely associated with dementia. High level of LDL-C may be considered as a potential protective factor against cognition decline.

    https://www.frontiersin.org/articles/10.3389/fneur.2018.00952/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE


    _________________
    I'm a skinny T2 diagnosed 4/4/2008, a high calorie LCHF diet and one metformin a day A1c 6.2 and no complications.

    Proving the LowCarb sceptics wrong for over ten years

    Not all cherubs are Angels  Wink nor all diabetics Bonkers  Rolling Eyes
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    chris c
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    Re: More Science, Can You Believe It?

    Post by chris c Yesterday at 23:27

    Didn't you just post the second one? Are you getting demented? hahahahaha oh I see the full version has now been published

    The first one looks good, Cara Ebbeling and David Ludwig. Wait for the replies from the usual low carb antis.

    James Di Nicolantonio has been busy too

    Good Fats versus Bad Fats:
    A Comparison of Fatty Acids in the Promotion
    of Insulin Resistance, Inflammation, and Obesity

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140086/pdf/ms114_p0303.pdf

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