THE LOW CARB DIABETIC

Would you like to react to this message? Create an account in a few clicks or log in to continue.
THE LOW CARB DIABETIC

Promoting a low carb high fat lifestyle for the safe control of diabetes. Eat whole fresh food, more drugs are not the answer.


Welcome to the Low Carb Diabetic forum,have you signed up yet? if not then sign up and join us in the low carb community today!

4 posters

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    yoly
    yoly
    Member


    Status :
    Online
    Offline

    Posts : 650
    Join date : 2014-08-14

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes Empty Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    Post by yoly Sun Feb 07 2016, 12:33

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    Published: February 5, 2016.
    Released by Federation of American Societies for Experimental Biology

    There may be a genetic connection between some mental health disorders and type 2 diabetes. In a new report appearing in the February 2016 issue of The FASEB Journal, scientists show that a gene called "DISC1," which is believed to play a role in mental health disorders, such as schizophrenia, bipolar disorder and some forms of depression, influences the function of pancreatic beta cells which produce insulin to maintain normal blood glucose levels.

    "Studies exploring the biology of disease have increasingly identified the involvement of unanticipated proteins--DISC1 fits this category," said Rita Bortell, Ph.D., a researcher involved in the work from the Diabetes Center of Excellence at the Universityof Massachusetts Medical School in Worcester, Massachusetts. "Our hope is that the association we've found linking disrupted DISC1 to both diabetes and psychiatric disorders may uncover mechanisms to improve therapies, even preventative ones, to alleviate suffering caused by both illnesses which are extraordinarily costly, very common, often quite debilitating."

    To make their discovery, Bortell and colleagues studied the function of DISC1 by comparing two groups of mice. The first group was genetically manipulated to disrupt the DISC1 gene only in the mouse's pancreatic beta cells. The second group of mice was normal. The mice with disrupted DISC1 gene showed increased beta cell death, less insulin secretion and impaired glucose regulation while control mice were normal. The researchers found that DISC1 works by controlling the activity of a specific protein (GSK3β) already known to be critical for beta cell function and survival. Inhibition of GSK3β resulted in improved beta cell survival and restored normal glucose tolerance in mice with disrupted DISC1. Alterations in the DISC1 gene were originally associated with increased risk of schizophrenia, but further studies have also found DISC1 alterations in individuals with bipolar disorder and major depression.

    "The connections between these disorders may be surprising, but we have known for a long time that a single protein or gene can play multiple roles in the body," said Thoru Pederson, Ph.D., Editor-in-Chief of The FASEB Journal.

    http://www.sciencenewsline.com/news/2016020517490020.html
    Eddie
    Eddie
    Member


    Status :
    Online
    Offline

    Male Posts : 3807
    Join date : 2014-08-13
    Age : 74
    Location : London

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes Empty Re: Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    Post by Eddie Sun Feb 07 2016, 12:53

    "Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes"

    Jeez, I was planning to use that as my defence the next time I get a High Court threat from the BDA, thanks Yoly. thumb-up
    Eddie
    Eddie
    Member


    Status :
    Online
    Offline

    Male Posts : 3807
    Join date : 2014-08-13
    Age : 74
    Location : London

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes Empty Re: Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    Post by Eddie Sun Feb 07 2016, 14:26

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes 5501982754_0205c29ff3_b

    Have you considered the possibility these mouse studies are over-rated Mickey

    Have you got a caption for this image?
    chris c
    chris c
    Member


    Status :
    Online
    Offline

    Posts : 4520
    Join date : 2015-07-26

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes Empty Re: Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    Post by chris c Sun Feb 07 2016, 18:51

    "It's true! Farting in your general direction DOES cure diabetes in mice!"
    Paul1976
    Paul1976
    Moderator


    Status :
    Online
    Offline

    Male Posts : 2439
    Join date : 2014-08-12
    Age : 47
    Location : East midlands,UK

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes Empty Re: Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    Post by Paul1976 Sun Feb 07 2016, 19:04

    "I gotta confess Doc-I AM kinda burnt out right now...Taking part in all these studies in some blokes basement just to provide Phoenix with links is grueling..."
    chris c
    chris c
    Member


    Status :
    Online
    Offline

    Posts : 4520
    Join date : 2015-07-26

    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes Empty Re: Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    Post by chris c Sun Feb 07 2016, 19:14

    Ba-da-BING!

    Sponsored content


    Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes Empty Re: Scientists Discover Molecular Link Between Psychiatric Disorders And Type 2 Diabetes

    Post by Sponsored content


      Current date/time is Thu Mar 28 2024, 21:36